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KMID : 0978920070080020256
Korean Journal of Clinical Geriatrics
2007 Volume.8 No. 2 p.256 ~ p.263
Purple Urine Bag Syndrome in Geriatric Wards
Choi Kyu-Dong

Ga Hyuk
Park Ki-Ho
Yoo Byung-Ik
Kim Sung-Min
Kang Moon-Chul
Lee Eun-Jah
Park Seung-Tae
Abstract
Background: Since the first report of purple urine bag syndrome (PUBS) by Barlow and Dickson in 1978, many researchers have tried to reveal the clinical and bacteriological background of this phenomenon. To the best of our knowledge, most of them were case or case series reports and only three were case-control studies which compared the clinical, biochemical, or bacteriological background between patients with and without PUBS. It is certain that PUBS is an uncomfortable or troubling issue for some patients and their families. However, most of the patients who presented with
PUBS were, largely, asymptomatic and it is apparent that PUBS is not a disease per se, nor does it appear to represent any real danger to patient¡¯s health, and some authors go so far as to even advocate that it is unnecessary to treat PUBS-affected patients aggressively. In this case-control study, we reviewed risk factors and clinical significance of PUBS in geriatric wards.

Methods: Of the 381 hospitalized patients in a hospital specialized in the long term care of the elderly
handicapped (Incheon Eun-Hye Hospital, Incheon, Korea), 65 patients who featured urinary catheterization during the period from February 2007 and April 2007 were enrolled in this study. Subjects who were younger than 65 or catheterized duration was less than one month were excluded. The same types of silicone Foley balloon catheter and disposable plastic urine bag were used for all patients. Routine Foley catheter change interval was one month. For the 16 patients who exhibits PUBS, bladder irrigation with normal saline and immediate change of urine bag and catheter were performed. And
urine culture was done. Variables were statistically analyzed by chi square test or Mann-Whitney¡¯s U-test. P values less than 0.05 were considered statistically significant.

Results: The PUBS patients mean age was 80, and bed ridden female. Most common diagnosis was dementia. Mean duration of the catheterization was 22 months. The PUBS patients were more constipated than non-PUBS control group and used more bisacodyl suppository. Antibiotics usage within one month before this survey in PUBS group is more frequent than control group with borderline statistical significance.

Conclusion: PUBS is frequently occurring problem in long-term care geriatric wards. Causative factors are tryptophan putrefaction (decreased intestinal absorption, motility), alkaline urine, oxygen(air, Foley catheterization). All factors are bacterial infection related. Our results were the same as previous results. Relationship with antibiotics usage, bisacodyl suppository and constipation, long term usage of the Foley catheter notified also. Female predomination is related with easy, frequent urinary infection, and more population in old age.
KEYWORD
Purple urine bag syndrome (PUBS), Old aged, Long term catheterized patients, Characteristics of pubs patients
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